HMG-CoA Reductase Inhibitor

**Semantic type:** Chemical Viewed Functionally

**Definition:** Any substance that inhibits HMG-CoA reductase, a key enzyme in cholesterol synthesis. Inhibition of HMG-CoA reductase acts to lower plasma cholesterol and lipoprotein levels.

**Synonyms:** - HMG-CoA reductase inhibitor - Hydroxymethylglutaryl CoenzymeA Reductase Inhibitors - Statin - Statin - hydroxymethylglutaryl-coenzyme A reductase inhibitor - statin