Doravirine

**Semantic type:** Pharmacologic Substance

**Definition:** A pyridinone non-nucleoside reverse transcriptase inhibitor (NNRTI) of human immunodeficiency virus type 1 (HIV-1), that is used to treat HIV infection. Upon oral administration, doravirine non-competitively inhibits HIV-1 reverse transcriptase (RT), thereby inhibiting HIV-1 viral replication.

**Synonyms:** - DORAVIRINE - Pifeltro