Urokinase-Type Plasminogen Activator

**Semantic type:** Amino Acid, Peptide, or Protein|Enzyme

**Definition:** Urokinase-type plasminogen activator (431 aa, ~49 kDa) is encoded by the human PLAU gene. This protein plays a role in both cell surface receptor binding and the cleavage of plasminogen between Arg-580 and Val-581 to form the fibrinolytic enzyme plasmin.

**Synonyms:** - EC 3.4.21.73 - PLAU - Plasminogen Activator, Urinary - Plasminogen Activator, Urokinase - U-Plasminogen Activator - Urinary Plasminogen Activator - Urokinase - Urokinase Plasminogen Activator - u-PA - u-plasminogen activator - uPA - uPA - urokinase - urokinase-plasminogen activator