Eniluracil

**Semantic type:** Nucleic Acid, Nucleoside, or Nucleotide|Pharmacologic Substance

**Definition:** An orally-active fluoropyrimidine analogue. Eniluracil inhibits dihydropyrimidine dehydrogenase, the rate-limiting enzyme that catabolizes and inactivates 5-fluorouracil (5-FU) in the liver. Co-administration of ethynyluracil permits the oral administration of 5-FU.

**Synonyms:** - 5-Ethynyl-2,4(1H,3H)-pyrimidinedione - 5-Ethynyluracil - 5-Fluorouracil Enhancer - 5-ethynyluracil - 776C85 - ENILURACIL - GW776 - PCS 6422 - PCS-6422 - PCS6422 - eniluracil - ethynyluracil