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C17746Level 7

Multidrug Resistance Protein 1

**Semantic type:** Amino Acid, Peptide, or Protein|Enzyme

**Definition:** Multidrug resistance protein 1 (1280 aa, ~141 kDa) is encoded by the human ABCB1 gene. This protein plays a role in both ATP-dependent transport of xenobiotics and resistance to chemotherapeutics.

**Synonyms:** - ABCB1 - ATP-Binding Cassette Sub-Family B Member 1 - CD243 Antigen - EC 3.6.3.44, Formerly - EC 7.6.2.2 - MDR1 Protein - Multidrug Resistance 1 - P-Glycoprotein 1 - P-Glycoprotein Transporter - p-glycoprotein

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