ABC Transporter

**Semantic type:** Amino Acid, Peptide, or Protein

**Definition:** A family of transmembrane proteins that usually function as dimers to hydrolyze ATP, which permits them to transport a wide variety of substrates across cellular membranes. These proteins consist of two distinct domains, a transmembrane domain and a nucleotide-binding domain. ATP binding is required for both dimerization and transporter activity.

**Synonyms:** - ABC Transport Protein - ABC Transporter Protein - ATP Binding Cassette Transporter - ATP-Binding Cassette Transporter