TNF Receptor-Associated Factor 2

**Semantic type:** Amino Acid, Peptide, or Protein|Enzyme

**Definition:** TNF receptor-associated factor 2 (501 aa, ~56 kDa) is encoded by the human TRAF2 gene. This protein is involved in antibody isotype switching, protein ubiquitination, tumor necrosis factor receptor-dependent signaling, and the regulation of apoptosis.

**Synonyms:** - E3 Ubiquitin-Protein Ligase TRAF2 - EC 2.3.2.27 - EC 6.3.2.-, Formerly - TRAF2 - Tumor Necrosis Factor Type 2 Receptor Associated Protein 2 - Tumor Necrosis Factor Type 2 Receptor Associated Protein 3 - Tumor Necrosis Factor Type 2 Receptor-Associated Protein 2 - Tumor Necrosis Factor Type 2 Receptor-Associated Protein 3