Breast Cancer Type 1 Susceptibility Protein

**Semantic type:** Amino Acid, Peptide, or Protein|Enzyme

**Definition:** Breast cancer type 1 susceptibility protein (1863 aa, ~208 kDa) is encoded by the human BRCA1 gene. This protein plays a role in both the maintenance of DNA and the mediation of ubiquitin E3 ligase activity.

**Synonyms:** - BRCA1 - BRCA1 Protein - BRCA1/BRCA2-Containing Complex, Subunit 1 - Breast Cancer 1, Early Onset Protein - Breast and Ovarian Cancer Susceptibility Protein 1 - Breast-Ovarian Cancer Protein - EC 2.3.2.27 - EC 6.3.2.-, Formerly - Fanconi Anemia, Complementation Group S - Protein Phosphatase 1, Regulatory Subunit 53 - RING Finger Protein 53 - RING-Type E3 Ubiquitin Transferase BRCA1