Rho Guanine Nucleotide Exchange Factor 5

**Semantic type:** Amino Acid, Peptide, or Protein

**Definition:** Rho guanine nucleotide exchange factor 5 (1597 aa, ~177 kDa) is encoded by the human ARHGEF5 gene. This protein plays a role in the activation of Rho family GTPases.

**Synonyms:** - ARHGEF5 - Ephexin-3 - GEF5 - Guanine Nucleotide Regulatory Protein TIM - TIM - TIM1