Transmembrane Protease Serine 6

**Semantic type:** Amino Acid, Peptide, or Protein|Enzyme

**Definition:** Transmembrane protease serine 6 (811 aa, ~90 kDa) is encoded by the human TMPRSS6 gene. This protein is involved in the hydrolysis of hemojuvelin and matrix proteins, such as type I collagen, fibronectin and fibrinogen.

**Synonyms:** - EC 3.4.21.- - Matriptase 2 - Matriptase-2 - Membrane-Bound Mosaic Serine Proteinase Matriptase-2 - TMPRSS6 - Transmembrane Serine Protease 6 - Type II Transmembrane Serine Protease 6