E3 Ubiquitin-Protein Ligase Pellino Homolog 3

**Semantic type:** Amino Acid, Peptide, or Protein|Enzyme

**Definition:** E3 ubiquitin-protein ligase pellino homolog 3 (469 aa, ~51 kDa) is encoded by the human PELI3 gene. This protein plays a role in the covalent attachment of polyubiquitin onto interleukin-1 receptor-associated kinase 1.

**Synonyms:** - EC 2.3.2.27 - PELI3 - Pellino E3 Ubiquitin Protein Ligase Family Member 3 - Pellino Homolog 3 - Pellino-3 - Protein Pellino Homolog 3 - RING-Type E3 Ubiquitin Transferase Pellino Homolog 3