Phosphatidylinositol 3,4,5-Trisphosphate 3-Phosphatase and Dual-Specificity Protein Phosphatase PTEN

**Semantic type:** Amino Acid, Peptide, or Protein|Enzyme

**Definition:** Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN (403 aa, ~47 kDa) is encoded by the human PTEN gene. This protein plays a role in signaling and as both a dual-specificity phosphoprotein phosphatase and a lipid phosphatase.

**Synonyms:** - EC 3.1.3.16 - EC 3.1.3.48 - EC 3.1.3.67 - Mitochondrial PTENalpha - Mitochondrial Phosphatase and Tensin Protein Alpha - Mutated in Multiple Advanced Cancers 1 - PTEN - PTEN - PTEN - PTEN Tyrosine Phosphatase - PTEN tyrosine phosphatase - Phosphatase and Tensin Homolog - Phosphatase and Tensin-Like Protein - Phosphatidylinositol-3,4,5-Trisphosphate 3-Phosphatase and Dual-Specificity Protein Phosphatase PTEN