Caspase-8

**Semantic type:** Amino Acid, Peptide, or Protein|Enzyme

**Definition:** Caspase-8 (479 aa, ~55 kDa) is encoded by the human CASP8 gene. This protein plays a role in proteolysis, angiogenesis and caspase-induction of apoptosis.

**Synonyms:** - Apoptotic Cysteine Protease - Apoptotic Protease Mch-5 - CAP4 - CASP-8 - CASP8 - CASP8 Protein - Caspase 8 - Caspase-8/Flice - EC 3.4.22.61 - FADD-Homologous ICE/ced-3-Like Protease - FADD-Like ICE - FADD-homologous ICE/CED3-Like Protease - FLICE - ICE-Like Apoptotic Protease 5 - MACH - MCH5 - MORT1-Associated ced-3 Homolog