E3 Ubiquitin-Protein Ligase SMURF2

**Semantic type:** Amino Acid, Peptide, or Protein|Enzyme

**Definition:** E3 ubiquitin-protein ligase SMURF2 (748 aa, ~86 kDa) is encoded by the human SMURF2 gene. This protein is involved in the modulation of SMAD/TGF-beta receptor complex degradation.

**Synonyms:** - E3 Ubiquitin Ligase SMURF2 - EC 2.3.2.26 - HECT-Type E3 Ubiquitin Transferase SMURF2 - SMAD Specific E3 Ubiquitin Protein Ligase 2 - SMAD Ubiquitination Regulatory Factor 2 - SMAD-Specific E3 Ubiquitin-Protein Ligase 2 - SMURF2 - hSMURF2