Rap Guanine Nucleotide Exchange Factor 2

**Semantic type:** Amino Acid, Peptide, or Protein

**Definition:** Rap guanine nucleotide exchange factor 2 (1499 aa, ~167 kDa) is encoded by the human RAPGEF2 gene. This protein is involved in regulation of signaling downstream of ligand-activated beta-1 adrenergic receptor.

**Synonyms:** - CNrasGEF - Cyclic Nucleotide Ras GEF - Neural RAP Guanine Nucleotide Exchange Protein - PDZ Domain-Containing Guanine Nucleotide Exchange Factor 1 - PDZ-GEF1 - RA-GEF-1 - RAPGEF2 - Ras-Associating Guanine Nucleotide Exchange Factor - Ras/Rap1-Associating GEF-1 - nRap GEP