Ubiquitin Carboxyl-Terminal Hydrolase 1

**Semantic type:** Amino Acid, Peptide, or Protein|Enzyme

**Definition:** Ubiquitin carboxyl-terminal hydrolase 1 (785 aa, ~88 kDa) is encoded by the human USP1 gene. This protein is involved in the deubiquitination of certain monoubiquitinated DNA repair proteins, including proliferating cell nuclear antigen (PCNA) and Fanconi anemia group D2 protein (FANCD2).

**Synonyms:** - Deubiquitinating Enzyme 1 - EC 3.4.19.12 - USP1 - Ubiquitin Specific Peptidase 1 - Ubiquitin Specific Processing Protease 1 - Ubiquitin Specific Protease 1 - Ubiquitin Thioesterase 1 - Ubiquitin Thiolesterase 1 - Ubiquitin-Specific Protease 1 - Ubiquitin-Specific-Processing Protease 1 - hUBP