C185935Level 8
Diffuse Glioneuronal Tumor with Oligodendroglioma-Like Features and Nuclear Clusters
**Semantic type:** Neoplastic Process
**Definition:** A provisional tumor entity described in the supratentorial brain and characterized by a distinct DNA methylation profile and monosomy of chromosome 14. It is composed of small to medium-sized cells showing perinuclear oligodendroglioma-like haloes, scattered multinucleated cells, and nuclear clusters composed of large pleomorphic nuclei. Most cases have been reported in pediatric patients.
**Synonyms:** - DGONC
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