Activating EGFR Exon 19 Deletion Mutation

**Semantic type:** Cell or Molecular Dysfunction

**Definition:** A molecular genetic abnormality indicating the presence of a deletion mutation in exon 19 of the EGFR gene that results in constitutive epidermal growth factor receptor-dependent signal transduction and activation of downstream signaling pathways.

**Synonyms:** - Activating EGFR Ex19Del Mutation - Activating EGFR Exon 19 Gene Deletion Mutation - Activating ERBB Exon 19 Deletion Mutation - Activating ERBB1 Exon 19 Deletion Mutation - Activating Epidermal Growth Factor Receptor Exon 19 Deletion Mutation - Activating Ex19Del Mutation - Activating HER1 Exon 19 Deletion Mutation - EGFR Exon 19 Activating Deletion Mutation - EGFR Exon 19 Activating Gene Deletion Mutation - Gain of Function EGFR Exon 19 Deletion Mutation - Gain of Function EGFR Exon 19 Gene Deletion Mutation