Epipodophyllotoxin Analog GL331

**Semantic type:** Organic Chemical|Pharmacologic Substance

**Definition:** An epipodophyllotoxin analogue possessing antineoplastic properties. GL331 binds to and inhibits topoisomerase II, resulting in the accumulation of single- or double-strand DNA breaks, the inhibition of DNA replication and transcription, and apoptotic cell death. (NCI)

**Synonyms:** - GL331