Lung Small Cell Carcinoma, I Subtype

**Semantic type:** Neoplastic Process

**Definition:** A molecular subtype of lung small cell carcinoma characterized by the low expression of achaete-scute homolog 1 (ASCL1), neurogenic differentiation factor 1 (NEUROD1), and POU class 2 homeobox 3 (POU2F3) transcription factor signatures and elevated inflammatory gene signature expression.

**Synonyms:** - Lung Small Cell Carcinoma, Inflamed Subtype - SCLC-I