Recombinant Tumor Necrosis Factor Family Protein

**Semantic type:** Chemical Viewed Functionally

**Definition:** A recombinant therapeutic agent which is chemically identical to or similar to one of a number of endogenous tumor necrosis factor (TNF) proteins. TNF family cytokines bind to and activate specific cell-surface receptors, thereby mediating inflammatory processes, cell proliferation, immunity, angiogenesis, and tumor cell cytotoxicity. One primary antitumor effect of TNFs involves stimulation of T cell-mediated antitumor cytotoxicity.

**Synonyms:** - TNF - Tumor Necrosis Factor Family Protein - Tumor Necrosis Factors - tumor necrosis factor