Recombinant Tumor Necrosis Factor-Beta

**Semantic type:** Amino Acid, Peptide, or Protein|Pharmacologic Substance

**Definition:** A recombinant agent, which is chemically identical to or similar to the endogenous cytokine tumor necrosis factor-beta (TNF-beta). Produced predominantly by T-lymphocytes and leukocytes, TNF-beta is cytolytic or cytostatic for many tumor cells, and can inhibit the growth of endothelial cells, resulting in an antiangiogenic effect. (NCI04)

**Synonyms:** - Lymphotoxin - Lymphotoxin - Lymphotoxin A - Lymphotoxin-Alpha - TNF beta - Tumor Necrosis Factor-Beta