Mitochondrial M2 Antigen

**Semantic type:** Amino Acid, Peptide, or Protein|Immunologic Factor

**Definition:** Antigen(s) of the inner mitochondrial membrane proteins, with a designation of M2, and may be comprised of (but not limited to) protein X, the E2 component, E1a and E1b subunits of the pyruvate dehydrogenase complex (PDC). They can be considered as autoantigens and are commonly associated with autoimmune hepatitis and primary biliary cholangitis/cirrhosis.

**Synonyms:** - M2 Antigen - M2 Antigen Complex - M2 Complex Antigen - MITOCHONDRIAL M2 - Mitochondrial Antigen M2 - Mitochondrial Autoantigen M2 - Mitochondrial M2 Complex Antigen