Inositol Polyphosphate 5-Phosphatase OCRL

**Semantic type:** Amino Acid, Peptide, or Protein|Enzyme

**Definition:** Inositol polyphosphate 5-phosphatase OCRL (901 aa, ~104 kDa) is encoded by the human OCRL gene. This protein is involved in the hydrolysis of the 5-position phosphate of phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), phosphatidylinositol-3,4,5-bisphosphate (PtdIns(3,4,5)P3), inositol 1,4,5-trisphosphate and inositol 1,3,4,5-tetrakisphosphate.

**Synonyms:** - EC 3.1.3.36 - EC 3.1.3.56 - EC 3.1.3.86 - Inositol Polyphosphate 5-Phosphatase OCRL-1 - Lowe Oculocerebrorenal Syndrome Protein - OCRL - OCRL Inositol Polyphosphate-5-Phosphatase - OCRL-1 - Phosphatidylinositol 3,4,5-Triphosphate 5-Phosphatase