Transforming Growth Factor-Beta Superfamily

**Semantic type:** Amino Acid, Peptide, or Protein

**Definition:** A family of structurally-related cytokines that bind to their cognate serine/threonine kinase receptors as homodimers or heterodimers linked by a single disulfide bond. These proteins play a role in embryonic development, hematopoiesis, tissue repair and extracellular matrix remodeling.

**Synonyms:** - Bone-Derived Transforming Growth Factor - Milk Growth Factor - TGF B - TGF Beta - TGF-B - TGF-Beta - Transforming Growth Factor Beta - Transforming Growth Factor-Beta - Tumor Growth Factor B - Tumor Growth Factor Beta