PPP2R2B wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human PPP2R2B wild-type allele is located in the vicinity of 5q32 and is approximately 504 kb in length. This allele, which encodes serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform protein, is involved in the regulation of protein phosphatase activity. Expansion of a CAG trinucleotide repeat sequence in the 5' UTR of the gene from 7-28 copies to 55-78 copies is associated with autosomal dominant spinocerebellar ataxia 12.

**Synonyms:** - B55-BETA - B55BETA - PP2AB-BETA - PP2AB55-BETA - PP2AB55BETA - PP2ABBETA - PP2APR55-BETA - PP2APR55B - PP2APR55BETA - PR2AB55BETA - PR2ABBETA - PR2APR55BETA - PR52B - PR55-BETA - PR55BETA - Protein Phosphatase 2 (Formerly 2A), Regulatory Subunit B (PR 52), Beta Isoform Gene - Protein Phosphatase 2 Regulatory Subunit Bbeta wt Allele - Protein Phosphatase 2, Regulatory Subunit B, Beta Gene - SCA12 - Spinocerebellar Ataxia 12 Gene