MHC Class I Protein

**Semantic type:** Amino Acid, Peptide, or Protein|Immunologic Factor

**Definition:** Found on virtually every cell, MHC (Major Histocompatibility, HLA) Class-I (Antigens) Proteins consist of noncovalently bound polymorphic 44-kDa MHC membrane glycoprotein and nonpolymorphic 12-kDa b2-microglobulin. The HLA antigens are encoded by closely linked multiallelic genes of the HLA (MHC) complex, a region containing several genetic loci (HLA-A, -B, -C, -DP, -DQ, -DR, -MB, -MT, and -Te).

**Synonyms:** - Class I MHC Protein - Complex Class 1 - HLA CLASS I ANTIGENS - Histocompatibility Antigen, Class I - Human Leukocyte Antigen - MHC Class I Molecule - Major Histocompatibility Complex Class 1