Stage III Appendix Carcinoma AJCC v9

**Semantic type:** Neoplastic Process

**Definition:** Stage III includes: IIIA: (T1, N1, M0, Any G); (T2, N1, M0, Any G); IIIB: (T3, N1, M0, Any G); (T4, N1, M0, Any G); IIIC: Any T, N2, M0, Any G. T1: Tumor invades the submucosa (through the muscularis mucosa but not into the muscularis propria). T2: Tumor invades the muscularis propria. T3: Tumor invades through the muscularis propria into the subserosa or the mesoappendix. T4: Tumor invades the visceral peritoneum, including the acellular mucin or mucinous epithelium involving the serosa of the appendix or mesoappendix, and/or directly invades adjacent organs or structures. N1: Tumor involvement of one to three regional lymph nodes (tumor in lymph node measuring greater than or equal to 0.2 mm) or any number of tumor deposits is present with no tumor involvement in all identifiable lymph nodes. N2: Tumor involvement of four or more regional lymph nodes. M0: No distant metastasis. (AJCC 9th ed.)

**Synonyms:** - Stage III Appendiceal Carcinoma AJCC v9