Mitochondrial Inner Membrane m-AAA Protease Component Paraplegin

**Semantic type:** Amino Acid, Peptide, or Protein|Enzyme

**Definition:** Mitochondrial inner membrane m-AAA protease component paraplegin (795 aa, ~88 kDa) is encoded by the human SPG7 gene. This protein is involved in both proteolysis and the formation and regulation of the mitochondrial permeability transition pore.

**Synonyms:** - Cell Matrix Adhesion Regulator - EC 3.4.24.- - Paraplegin - SPG7 - Spastic Paraplegia 7 Protein