World Of Taxonomy
C2085Level 5

Chlorodihydropyrimidine

**Semantic type:** Organic Chemical|Pharmacologic Substance

**Definition:** A pyrimidine derivative with antitumor activity. Chlorodihydropyrimidine competitively and reversibly inhibits dihydropyrimidine dehydrogenase, a rate-limiting enzyme in the catabolism of fluoropyrimidines thereby blocking the degradation of the fluoropyrimidines.

**Synonyms:** - 5-Chlorodihydropyrimidine

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