Ornithine Decarboxylase Inhibitor

**Semantic type:** Chemical Viewed Functionally

**Definition:** Any substance that inhibits ornithine decarboxylase, an enzyme that catalyzes the decarboxylation of ornithine, the rate-limiting, commiting reaction in polyamine synthesis. Polyamines are important for stabilizing DNA structure, for the DNA double strand-break repair pathway, and as antioxidants, and inhibition of ornithine decarboxylase inhibits cell growth.

**Synonyms:** - Ornithine Decarboxylase Inhibitors