Rho Guanine Nucleotide Exchange Factor 1

**Semantic type:** Amino Acid, Peptide, or Protein

**Definition:** Rho guanine nucleotide exchange factor 1 (912 aa, ~102 kDa) is encoded by the human ARHGEF1 gene. This protein plays a role in the regulation of transforming protein RhoA-dependent signaling.

**Synonyms:** - 115 kDa Guanine Nucleotide Exchange Factor - ARHGEF1 - Lsc Homolog - Rho GEF 1 - Sub1.5 - p115-RHOGEF - p115RhoGEF