C2134Level 4

O6-Alkylguanine-DNA Alkyltransferase Inhibitor

**Semantic type:** Chemical Viewed Functionally

**Definition:** Any substance that inhibits O6-Alkylguanine-DNA alkyltransferase, a DNA repair enzyme that catalyzes the removal of alkyl groups from DNA. Inhibition of O6-Alkylguanine-DNA alkyltransferase increases the effectiveness of DNA alkylating agents.

**Synonyms:** - Alkyl-Guanine Transferase Inhibitor - O6-Alkylguanine-DNA Alkyltransferase Inhibitors

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C1306O6-Benzylguanine

C2653Laromustine

C66028Lomeguatrib

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