HLA Class I Histocompatibility Antigen, B-27 Alpha Chain

**Semantic type:** Amino Acid, Peptide, or Protein

**Definition:** HLA class I histocompatibility antigen, B-27 alpha chain (362 aa, ~40 kDa) is encoded by the human HLA-B gene. This protein is involved in the presentation of viral epitopes to CD8-positive T-lymphocytes. Expression of this serotype is associated with ankylosing spondylitis and other inflammatory diseases.

**Synonyms:** - HLA Class I Histocompatibility Antigen, B*27 Alpha Chain - HLA-B Class I Antigen 27 - HLA-B Histocompatibility Type Antigen 27 - HLA-B*27 - HLA-B27 - HLA-B27 - HLA-B27 ANTIGEN - HLA-B27 Antigen - Human Leukocyte Antigen B27 - MHC Class I Antigen B*27 - Major Histocompatibility Complex, Class I, B27 Antigen