Endothelial-Specific Integrin/Survival Signaling Inhibitor

**Semantic type:** Chemical Viewed Functionally

**Definition:** An angiogenesis inhibitor that acts by blocking the action of endothelial integrins. An endothelial-specific integrin/survival signaling inhibitor binds to and blocks the activity of endothelial-specific integrins, thereby inhibiting endothelial cell-cell interactions, endothelial cell-matrix interactions, and angiogenesis.