Ubiquitin Carboxyl-Terminal Hydrolase 8

**Semantic type:** Amino Acid, Peptide, or Protein|Enzyme

**Definition:** Ubiquitin carboxyl-terminal hydrolase 8 (1118 aa, ~128 kDa) is encoded by the human USP8 gene. This protein plays a role in both protein deubiquitination and the inhibition of protein degradation.

**Synonyms:** - Deubiquitinating Enzyme 8 - Deubiquitinating Enzyme HUMORF8 - EC 3.4.19.12 - USP8 - Ubiquitin Isopeptidase Y - Ubiquitin Specific Protease 8 - Ubiquitin Thiolesterase 8 - Ubiquitin-Specific Processing Protease 8 - hUBPy