Rho Guanine Nucleotide Exchange Factor 3

**Semantic type:** Amino Acid, Peptide, or Protein

**Definition:** Rho guanine nucleotide exchange factor 3 (526 aa, ~60 kDa) is encoded by the human ARHGEF3 gene. This protein plays a role in the regulation of guanine nucleotide exchange to regulate GTPase-dependent signaling.

**Synonyms:** - ARHGEF3 - Exchange Factor Found in Platelets and Leukemic and Neuronal Tissues - XPLN