E3 Ubiquitin-Protein Ligase UBR1

**Semantic type:** Amino Acid, Peptide, or Protein|Enzyme

**Definition:** E3 ubiquitin-protein ligase UBR1 (1749 aa, ~200 kDa) is encoded by the human UBR1 gene. This protein plays a role in the polyubiquitination of N-terminal residues in specific protein substrates.

**Synonyms:** - EC 2.3.2.27 - N-Recognin-1 - RING-Type E3 Ubiquitin Transferase UBR1 - UBR1 - Ubiquitin Protein Ligase E3 Component N-Recognin 1 - Ubiquitin-Protein Ligase E3-Alpha-1 - Ubiquitin-Protein Ligase E3-Alpha-I