E-Cadherin Staining Method

**Semantic type:** Laboratory Procedure

**Definition:** An immunohistochemical technique to detect E-Cadherin, a transmembrane glycoprotein that is localized in the adherens junctions of epithelial cells, using antibody to E-Cadherin. The loss of expression or function of E-Cadherin appears to be an important step in tumorigenic progression.

**Synonyms:** - CDH1 Staining Method - Cadherin-1 Staining Method - ECAD Staining Method - Ecadherin Staining Method