Polyoma Virus Middle T Staining Method

**Semantic type:** Laboratory Procedure

**Definition:** Polyoma virus encodes three proteins, the large T (PyLT), middle T (PymT), and small T (Pyst) antigens, that bind p53 and thus block the function of p53. This immunohistochemical technique is used to identify metastasis-related genes using antibodies directed at Polyoma Virus Middle T antigen.

**Synonyms:** - PYMT Staining Method