Methylmercaptopurine Riboside

**Semantic type:** Nucleic Acid, Nucleoside, or Nucleotide|Pharmacologic Substance

**Definition:** A purine derivative with antineoplastic and anti-angiogenic properties. 6-methylmercaptopurine riboside (6-MMPR) inhibits amidophosphoribosyltransferase, the first committed step in de novo purine synthesis, and inhibits fibroblast growth factor-2 (FGF2)-induced cell proliferation. (NCI04)

**Synonyms:** - 6-(methylmercapto)purine ribonucleoside - 6-(methylthio) inosine - 6-(methylthio)purine ribonucleoside - 6-(methylthio)purine riboside - 6-MMPR - 6-MMPR - 6-methyl MP riboside - 6-methylmercaptopurine riboside - 6-methylthioinosine - 9H-Purine, 6-(methylthio)-9-.beta.-D-ribofuranosyl- (8CI 9CI) - 9H-Purine, 6-(methylthio)-9-.beta.-D-ribofuranosyl-, dihydrate - 9H-purine, 6-(methylthio)-9-beta-D-ribofuranosyl- (8CI 9CI) - 9H-purine, 6-(methylthio)-9-beta-D-ribofuranosyl-, dihydrate - 9H-purine, 6-(methylthio)-9beta-D-ribofuranosyl - METHYLTHIOINOSINE - MMPR - NCI-C04784 - SQ 21977 - beta-D-ribosyl-6-methylthiopurine - methylthioinosine - purine-6-thiol,6-methyl-9-ribofuranosyl