Liposomal Cytarabine

**Semantic type:** Nucleic Acid, Nucleoside, or Nucleotide|Pharmacologic Substance

**Definition:** A liposomal intrathecal formulation of the antimetabolite cytarabine. As an S-phase-specific antimetabolite, cytarabine is phosphorylated by deoxycytidine kinase to a triphosphate form which competes with thymidine for incorporation into DNA; the incorporation of cytarabine triphosphate into DNA appears to inhibit DNA polymerase and so DNA synthesis, resulting in cell death. (NCI04)

**Synonyms:** - Cytarabine Liposomal - Cytarabine Liposome - Cytarabine liposomal - DTC 101 - Depo-Cyt - DepoCyt - DepoCyte - DepoFoam Encapsulated Cytarabine - Encapsulated Cytarabine - Liposomal Ara-C - Liposomal cytarabine - cytarabine liposome - liposomal cytarabine