At 211 Monoclonal Antibody 81C6

**Semantic type:** Amino Acid, Peptide, or Protein|Pharmacologic Substance

**Definition:** A radioimmunoconjugate of a human-murine chimeric IgG2 monoclonal antibody (MoAb) 81C6 labeled with an alpha-emitting radionuclide Astatine 211 (At-211), with imaging and radioimmunotherapeutic properties. MoAb 81C6 recognizes the extracellular matrix antigen tenascin (hexabrachion), which is up-regulated in gliomas and other cancers. Using MoAb 81C6 as a carrier for At-211 results in the targeted imaging and/or destruction of cells expressing tenascin.

**Synonyms:** - Astatine 211 Conjugated 81C6 Anti-Tenascin Monoclonal Antibody - Astatine At 211 MOAB 81C6 - Astatine At 211 Monoclonal Antibody 81C6 - Astatine-211 Labelled Anti-Tenascin Monoclonal Antibody 81C6