C200225Level 5

Targeted Alpha Therapy Agent

**Semantic type:** Chemical Viewed Functionally

**Definition:** Any radiopharmaceutical agent that targets cancer cells and the tumor microenvironment (TME) and exerts an antineoplastic effect through alpha particles.

**Synonyms:** - TAT Agent

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C133190Astatine At 211 Anti-CD45 Monoclonal Antibody BC8-B10

C155977Thorium Th 227 Anetumab Corixetan

C158815Actinium Ac 225-FPI-1434

C165280Astatine At 211 Anti-CD38 Monoclonal Antibody OKT10-B10

C168996Thorium Th 227 Trastuzumab Corixetan

C175301Thorium Th 227 Pelgifatamab Corixetan

C176627Actinium Ac 225-DOTA-h11B6 JNJ-69086420

C178329Astatine At 211 F(ab')2 MX35

C185145Actinium Ac 225-DOTA-anti-CEA Monoclonal Antibody M5A

C186744Actinium Ac 225-DOTA-Daratumumab

C187702Actinium Ac 225 Vofatamab

C206445Actinium Ac 225 FPI-2068

C211713Actinium Ac 225 Alpitatug Satetraxetan

C213967Actinium-225-labeled PSMA Radioligand

C214889Actinium Ac 225-ABD147

C220241Actinium Ac 225-DOTA-Anti-STEAP2 Monoclonal Antibody AZD2284

C2490At 211 Monoclonal Antibody 81C6

C28502Bismuth Bi213 Monoclonal Antibody M195

C62535Radium Ra 223 Dichloride

C82414Actinium Ac 225 Lintuzumab

C97500Lead Pb 212 TCMC-trastuzumab

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