13-Deoxydoxorubicin

**Semantic type:** Organic Chemical|Pharmacologic Substance

**Definition:** An analogue of the anthracycline antineoplastic antibiotic doxorubicin. 13-Deoxydoxorubicin intercalates DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair and RNA and protein synthesis. This agent was designed to be a non-cardiotoxic anthracycline antibiotic.

**Synonyms:** - 13-DEOXYDOXORUBICIN - GPX-100 - GPX-100 - GPX100