Recombinant Fowlpox-CEA(6D)/TRICOM Vaccine

**Semantic type:** Immunologic Factor|Pharmacologic Substance|Virus

**Definition:** A cancer vaccine comprised of a recombinant fowlpox virus vector encoding the carcinoembryonic antigen (CEA) and a TRIad of COstimulatory Molecules (B7-1, ICAM-1 and LFA-3) (TRICOM). This agent may enhance CEA presentation to antigen presenting cells (APC) and activate cytotoxic T-cells against CEA-expressing tumors. (NCI04)

**Synonyms:** - Recombinant Fowlpox-CEA-TRICOM Vaccine - fowlpox-CEA-B7.1/ICAM-1/LFA-3 - rF-CEA(6D)TRICOM