Recombinant Fowlpox-TRICOM Vaccine

**Semantic type:** Chemical Viewed Functionally

**Definition:** A vaccine comprised of a recombinant fowlpox virus vector encoding a TRIad of COstimulatory Molecules (B7-1, ICAM-1 and LFA-3) (TRICOM), which may enhance antigen presentation and activate cytotoxic T-cells. Fowlpox virus is an attractive vector because its genome is easy to manipulate and it is replication incompetent in mammalian cells. (NCI04)

**Synonyms:** - Recombinant Fowlpox-TRICOM - rF-TRICOM - rF-TRICOM (B7.1.iCAM1-LFA3-Fowlpox) - recombinant fowlpox-TRICOM vaccine