Soblidotin

**Semantic type:** Pharmacologic Substance

**Definition:** A dolastatin-10 derivative. Soblidotin inhibits tubulin polymerization, resulting in cell cycle arrest and induction of apoptosis. (NCI04)

**Synonyms:** - Auristatin PE - N(2)-(N,N-Dimethyl-valyl)-N-(2-methoxy-4-(2-(1-methoxy-2-methyl-3-oxo-3-((2-phenylethyl)amino)propyl)-1-pyrrolidinyl)-1-(1-methylpropyl)-4-oxobutyl)-N-methyl-valinamide - SOBLIDOTIN - TZT-1027 - TZT-1027 - soblidotin