Nab-paclitaxel

**Semantic type:** Pharmacologic Substance

**Definition:** A Cremophor EL-free, albumin-stabilized nanoparticle formulation of the natural taxane paclitaxel with antineoplastic activity. Paclitaxel binds to and stabilizes microtubules, preventing their depolymerization and so inhibiting cellular motility, mitosis, and replication. This formulation solubilizes paclitaxel without the use of the solvent Cremophor, thereby permitting the administration of larger doses of paclitaxel while avoiding the toxic effects associated with Cremophor.

**Synonyms:** - ABI 007 - ABI-007 - ABI-007 - ABI007 - Abraxane - Abraxane - Albumin-Stabilized Nanoparticle Paclitaxel - Albumin-bound Paclitaxel - Nanoparticle Albumin-bound Paclitaxel - Nanoparticle Paclitaxel - Naveruclif - Paclitaxel Albumin - Paclitaxel Nanoparticle Albumin-bound - Paclitaxel Protein-Bound - Paclitaxel nanoparticle albumin-bound - Protein-bound Paclitaxel - nanoparticle paclitaxel - paclitaxel albumin-stabilized nanoparticle formulation - protein-bound paclitaxel