Bactobolin

**Semantic type:** Antibiotic|Organic Chemical|Pharmacologic Substance

**Definition:** A 3-dichloromethylactinobolin antineoplastic antibiotic isolated from various Pseudomonas bacterial species. BN-183 induces apoptosis via a caspase-dependent pathway. This agent also has immunomodulatory properties. (NCI04)

**Synonyms:** - (-)-Bactobolin - 2-Amino-N-[3-(dichloromethyl)-3,4,4a,5,6,7- hexahydro-5,6,8-trihydroxy-3-methyl-1-oxo-1H-2- benzopyran-4-yl], Propanamide - Antibiotic BN 183B - BACTOBOLIN - BN 183B - Y 12278